BDBM50223963 8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thiophen-3-yl)carbamate::CHEMBL236654

SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccccc1)c1ccsc1

InChI Key InChIKey=HVRWHBXGKRCKSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223963   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223963(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thi...)
Affinity DataIC50:  19.1nMAssay Description:Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223963(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thi...)
Affinity DataIC50:  39.1nMAssay Description:Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223963(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thi...)
Affinity DataIC50:  10.9nMAssay Description:Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed