BDBM50224385 1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL401238

SMILES CSc1nc(Nc2ccccc2)c2cnn(CC(Cl)c3ccccc3)c2n1

InChI Key InChIKey=JYRWBVRMNWJXEK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50224385   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50224385(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition human recombinant cSRC using KVEKIGEGTYGVVYK peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed