BDBM50224403 8-(4-methylphenyl)-1H-pyrazolo[3'',4'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-7(8H)-one::CHEMBL238262

SMILES Cc1ccc(cc1)-n1cnc2c(sc3ncc4c[nH]nc4c23)c1=O

InChI Key InChIKey=AJSOPCTYDMXEJW-UHFFFAOYSA-N

Data  1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224403   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50224403(8-(4-methylphenyl)-1H-pyrazolo[3'',4'':4',5']pyrid...)
Show SMILES Cc1ccc(cc1)-n1cnc2c(sc3ncc4c[nH]nc4c23)c1=O
Show InChI InChI=1S/C17H11N5OS/c1-9-2-4-11(5-3-9)22-8-19-14-12-13-10(7-20-21-13)6-18-16(12)24-15(14)17(22)23/h2-8H,1H3,(H,20,21)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human mGluR1a expressed in CHO cells assessed by measuring intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair