BDBM50225169 2-chloro-N-(4-{[(4R)-3'-(4,5-dihydro-1H-imidazol-2-yl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-en-1-yl]carbonyl}-2-methoxyphenyl)-5-fluorobenzamide::CHEMBL400860

SMILES COc1cc(ccc1NC(=O)c1cc(F)ccc1Cl)C(=O)N1CC[C@@]2(CCC(=C2)C2=NCCN2)Cc2ccccc12

InChI Key InChIKey=YHIQDROWCNXSMH-YTTGMZPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225169   

TargetVasopressin V1a receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225169(2-chloro-N-(4-{[(4R)-3'-(4,5-dihydro-1H-imidazol-2...)
Affinity DataIC50:  320nMAssay Description:Antagonist activity at human vasopressin V1a receptor expressed in HEK293 cells assessed as inhibition of Arg-vasopressin-induced intracllular calciu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225169(2-chloro-N-(4-{[(4R)-3'-(4,5-dihydro-1H-imidazol-2...)
Affinity DataIC50:  1.05E+3nMAssay Description:Antagonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as inhibition of Arg-vasopressin-induced cAMP levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed