BDBM50227147 2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL253731

SMILES OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3ccnc4c(cccc34)C(F)(F)F)cccc12

InChI Key InChIKey=YLJKCCPSAPDTDJ-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50227147   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227147(2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)...)
Affinity DataEC50:  622nMAssay Description:Agonist activity at human LXRbeta expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227147(2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)...)
Affinity DataIC50:  15nMAssay Description:Binding affinity at human LXRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227147(2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)...)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human recombinant PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227147(2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)...)
Affinity DataEC50:  1.19E+3nMAssay Description:Agonist activity at human LXRalpha expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227147(2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)...)
Affinity DataIC50:  745nMAssay Description:Binding affinity at human LXRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed