BDBM50228246 Indolidan

SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1

InChI Key InChIKey=LZCQFJKUAIWHRW-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228246   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228246(Indolidan)
Affinity DataKi:  5.40nMAssay Description:Displacement [3H]LY-186,126 from phosphodiesterase 4 of myocardial vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228246(Indolidan)
Affinity DataIC50:  80nMAssay Description:Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228246(Indolidan)
Affinity DataIC50:  150nMAssay Description:Inhibition of sarcoplasmic reticulum Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228246(Indolidan)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed