BDBM50234898 CHEMBL4068357::D3RKN_91

SMILES C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)N1CCCC1

InChI Key InChIKey=RONMOMUOZGIDET-HIFRSBDPSA-N

Data  8 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234898   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234898(CHEMBL4068357 | D3RKN_91)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of Tyk2 (unknown origin) using peptide substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234898(CHEMBL4068357 | D3RKN_91)
Affinity DataIC50:  128nMAssay Description:Inhibition of human TYK2 using 5FAM-KKSRGDYMTMQID as substrate by caliper microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed