BDBM50236025 CHEMBL2016761::US11149049, No. C2::US20240140975, Compound A109

SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N

InChI Key InChIKey=DFVPCNAMNAPBCX-LTGWCKQJSA-N

Data  7 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236025   

TargetGenome polyprotein(HCV)
Janssen Biopharma

US Patent
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2 | US20240140975...)
Affinity DataIC50:  1.00E+3nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetGenome polyprotein(DENV-1)
Janssen Biopharma

US Patent
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2 | US20240140975...)
Affinity DataIC50:  3.60E+3nMAssay Description:The enzyme activity of dengue virus NS5 polymerase domain (DENVpol, serotype 2, New Guinea C strain) was measured as an incorporation of tritiated NM...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2 | US20240140975...)
Affinity DataIC50:  270nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
In DepthDetails US Patent