BDBM50239168 CHEMBL4101219

SMILES Fc1cccc2[nH]cc(Cc3c[nH]c4cccc(F)c34)c12

InChI Key InChIKey=CBEURMZFFRNCJY-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239168   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239168(CHEMBL4101219)
Affinity DataEC50:  6.49E+3nMAssay Description:Antagonist activity at Gq protein coupled human FFAR1 expressed in human 1321N1 cells assessed as inhibition of TUG-424-induced intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239168(CHEMBL4101219)
Affinity DataEC50:  1.52E+3nMAssay Description:Positive allosteric modulation of recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as increase in [3H]PS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239168(CHEMBL4101219)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239168(CHEMBL4101219)
Affinity DataEC50:  328nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed