BDBM50239218 CHEMBL4104992

SMILES Fc1cc2c(Cc3c[nH]c4cc(Cl)c(F)cc34)c[nH]c2cc1Cl

InChI Key InChIKey=ULHDGVWUXSAKRH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239218   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239218(CHEMBL4104992)
Affinity DataEC50:  1.08E+4nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239218(CHEMBL4104992)
Affinity DataEC50:  129nMAssay Description:Positive allosteric modulation of recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as increase in [3H]PS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239218(CHEMBL4104992)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed