BDBM50240618 (2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide::CHEMBL76370::TEGASEROD

SMILES CCCCCNC(N)=NN=Cc1c[nH]c2ccc(OC)cc12

InChI Key InChIKey=IKBKZGMPCYNSLU-UHFFFAOYSA-N

Data  5 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240618   

Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  13nMAssay Description:Induction of 5-HT4 receptor-mediated contraction in guinea pig longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myenteric plexus assessed as contractionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  31nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity at 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed