BindingDB BDBM50240788 2-(2,5-dimethoxy-4-ethylphenyl)ethylamine::2-(4-Ethyl-2,5-dimethoxy-phenyl)-ethylamine::CHEMBL124063::US20240166618, Compound 2C-E

BDBM50240788 2-(2,5-dimethoxy-4-ethylphenyl)ethylamine::2-(4-Ethyl-2,5-dimethoxy-phenyl)-ethylamine::CHEMBL124063::US20240166618, Compound 2C-E

SMILES CCc1cc(OC)c(CCN)cc1OC

InChI Key InChIKey=VDRGNAMREYBIHA-UHFFFAOYSA-N

Data 50 KI 7 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 57 hits for monomerid = 50240788

Trace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 6.41E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair

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PubMed

5-hydroxytryptamine receptor 2C(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 1.08nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 2.5nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2C(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 0.233nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 3.16nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2C(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 0.642nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

EC50: 2.89nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 16.7nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2B(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 25.1nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 43.9nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1D(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 73.2nMMore data for this Ligand-Target Pair

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Alpha-2C adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 90.2nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 2C(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 104nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1B(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 253nMMore data for this Ligand-Target Pair

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Alpha-2B adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 306nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 307nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 7(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 426nMMore data for this Ligand-Target Pair

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Alpha-2A adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 490nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1E(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 626nMMore data for this Ligand-Target Pair

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d3-human(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 1.35E+3nMMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M5(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 1.73E+3nMMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 2.56E+3nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 6(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 2.97E+3nMMore data for this Ligand-Target Pair

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D(2) dopamine receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: 3.34E+3nMMore data for this Ligand-Target Pair

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Cannabinoid receptor 1(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M2(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Cannabinoid receptor 2(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Voltage-dependent calcium channel subunit alpha-2/delta-1(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Glutamate receptor ionotropic, NMDA 2A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 3A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Histamine H3 receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Histamine H4 receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Vasopressin V1a receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Vasopressin V1a receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Vasopressin V1b receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Gamma-aminobutyric acid receptor subunit alpha-1(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Gamma-aminobutyric acid receptor subunit alpha-1/Adenosine receptor A1(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Prostaglandin E2 receptor EP3 subtype(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Sodium-dependent noradrenaline transporter(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 5A(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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D(1A) dopamine receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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D(4) dopamine receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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D(1B) dopamine receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Alpha-1A adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Alpha-1B adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Beta-1 adrenergic receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Sodium-dependent serotonin transporter(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Sodium-dependent dopamine transporter(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Histamine H2 receptor(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Nischarin(Human)TBA

BDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Displayed 1 to 50 (of 57 total ) | Next | Last >>

Filter my 57 hits

Targets 49▿
- 5-hydroxytryptamine receptor 2A 5
- 5-hydroxytryptamine receptor 2C 4
- Vasopressin V1a receptor 2
- Sodium-dependent serotonin transporter 1
- Glutamate receptor ionotropic, NMDA 2A 1
- Sigma intracellular receptor 2 1
- Prostaglandin E2 receptor EP3 subtype 1
- Muscarinic acetylcholine receptor M5 1
- Sodium-dependent noradrenaline transporter 1
- Muscarinic acetylcholine receptor M4 1
- Nischarin 1
- Muscarinic acetylcholine receptor M3 1
- Muscarinic acetylcholine receptor M2 1
- Histamine H4 receptor 1
- Muscarinic acetylcholine receptor M1 1
- D(4) dopamine receptor 1
- Vasopressin V1b receptor 1
- Beta-1 adrenergic receptor 1
- Kappa-type opioid receptor 1
- Histamine H1 receptor 1
- 5-hydroxytryptamine receptor 1B 1
- D(2) dopamine receptor 1
- 5-hydroxytryptamine receptor 1A 1
- Delta-type opioid receptor 1
- 5-hydroxytryptamine receptor 3A 1
- Trace amine-associated receptor 1 1
- 5-hydroxytryptamine receptor 1E 1
- 5-hydroxytryptamine receptor 1D 1
- Mu-type opioid receptor 1
- d3-human 1
- Alpha-1A adrenergic receptor 1
- 5-hydroxytryptamine receptor 5A 1
- Gamma-aminobutyric acid receptor subunit alpha-1 1
- Histamine H3 receptor 1
- Alpha-2B adrenergic receptor 1
- Voltage-dependent calcium channel subunit alpha-2/delta-1 1
- Sodium-dependent dopamine transporter 1
- Alpha-2C adrenergic receptor 1
- Cannabinoid receptor 1 1
- Alpha-1B adrenergic receptor 1
- Gamma-aminobutyric acid receptor subunit alpha-1/Adenosine receptor A1 1
- 5-hydroxytryptamine receptor 2B 1
- D(1B) dopamine receptor 1
- D(1A) dopamine receptor 1
- 5-hydroxytryptamine receptor 7 1
- Cannabinoid receptor 2 1
- 5-hydroxytryptamine receptor 6 1
- Alpha-2A adrenergic receptor 1
- Histamine H2 receptor 1
Publications 2▿
- US Patent US20240166618 (2024) 1
- Bioorg Med Chem 16: 7415-23 (2008) 1
Institutions 2▿
- Gilgamesh Pharmaceuticals 1
- Rti International 1
Affinity: 0.23 to 1.0E+4 nM▿
- Ki 50
- EC50 7
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1