BDBM50240849 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine::1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine::4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline::CHEMBL1282::IMIQUIMOD::R 837

SMILES CC(C)Cn1cnc2c(N)nc3ccccc3c12

InChI Key InChIKey=DOUYETYNHWVLEO-UHFFFAOYSA-N

Data  5 IC50  8 EC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240849   

TargetToll-like receptor 7(Human)
University of Kansas

Curated by ChEMBL

LigandBDBM50240849(1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-ami...)Copy SMILESCopy InChI

Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLMCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI