BDBM50243345 CHEMBL451761::Tetrahydrofuran-2-ylmethyl{4-[({2-[(5-fluoropyridin-2-yl)carbonyl]phenyl}amino)sulfonyl]phenyl}carbamate

SMILES Fc1ccc(nc1)C(=O)c1ccccc1NS(=O)(=O)c1ccc(NC(=O)OCC2CCCO2)cc1

InChI Key InChIKey=DOCMMXGLCNAMKG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243345   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243345(CHEMBL451761 | Tetrahydrofuran-2-ylmethyl{4-[({2-[...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243345(CHEMBL451761 | Tetrahydrofuran-2-ylmethyl{4-[({2-[...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243345(CHEMBL451761 | Tetrahydrofuran-2-ylmethyl{4-[({2-[...)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of MK-499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243345(CHEMBL451761 | Tetrahydrofuran-2-ylmethyl{4-[({2-[...)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of MK-499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed