BDBM50244208 CHEMBL4093017

SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O

InChI Key InChIKey=AQCRJOWGCAFEAA-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50244208   

TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human mGlu2 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataIC50: 7.66E+3nMAssay Description:Antagonist activity at human mGlu2 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human mGlu3 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataKi:  425nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244208(CHEMBL4093017)
Affinity DataKi:  627nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed