BDBM50244209 CHEMBL4060567

SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)C1CCCCC1)C(O)=O

InChI Key InChIKey=URPILZHDNHGJFA-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50244209   

TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataEC50:  3.39E+3nMAssay Description:Agonist activity at human mGlu2 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at human mGlu2 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataIC50: 9.99E+3nMAssay Description:Antagonist activity at human mGlu3 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataKi:  757nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244209(CHEMBL4060567)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed