BDBM50244749 (S)-2-(5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-fluorophenoxy)propanoic acid::CHEMBL461379

SMILES C[C@H](Oc1cc(Cn2c(C)c(Oc3ccc(Cl)cc3)c3ccc(F)nc23)ccc1F)C(O)=O

InChI Key InChIKey=FPJDTUYZSJZOJL-AWEZNQCLSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244749   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244749((S)-2-(5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244749((S)-2-(5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity to PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244749((S)-2-(5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity to human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244749((S)-2-(5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1...)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed