BDBM50245478 CHEMBL4081588::US11472838, Compound Ref. 25

SMILES CCC(CC)CNC(=O)Cn1cccc(NC(=O)[C@H](CC\C=C\C(=O)OC)NC(=O)c2cncn2C)c1=O

InChI Key InChIKey=VHGWUSABWIEXKQ-BEBFYNPSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245478   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)

Curated by ChEMBL
LigandPNGBDBM50245478(CHEMBL4081588 | US11472838, Compound Ref. 25)
Affinity DataIC50:  45nMAssay Description:Inhibition of human TG2 using glycine methyl ester/Abz-APE as substrate after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)

Curated by ChEMBL
LigandPNGBDBM50245478(CHEMBL4081588 | US11472838, Compound Ref. 25)
Affinity DataIC50:  45nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
Zedira

US Patent
LigandPNGBDBM50245478(CHEMBL4081588 | US11472838, Compound Ref. 25)
Affinity DataIC50: >10nMAssay Description:FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2...More data for this Ligand-Target Pair
In DepthDetails US Patent