BDBM50247758 2-[(3-Phenyl-5'-(3-chlorophenyl)-2'-pyrazoline-1-yl]-3-methyl-4(3H)-quinazolinone::CHEMBL461960

SMILES Cn1c(nc2ccccc2c1=O)N1N=C(CC1c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=KUKFIJAZIBHMHL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247758   

TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247758(2-[(3-Phenyl-5'-(3-chlorophenyl)-2'-pyrazoline-1-y...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247758(2-[(3-Phenyl-5'-(3-chlorophenyl)-2'-pyrazoline-1-y...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247758(2-[(3-Phenyl-5'-(3-chlorophenyl)-2'-pyrazoline-1-y...)
Affinity DataKi:  900nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247758(2-[(3-Phenyl-5'-(3-chlorophenyl)-2'-pyrazoline-1-y...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed