BDBM50249293 (R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imidazol-2-yl)propyl dihydrogen phosphate::CHEMBL515917

SMILES C[C@](N)(COP(O)(O)=O)c1nc(c[nH]1)-c1ccc(OCCCCc2ccccc2)cc1

InChI Key InChIKey=GTROXDSLWCVOIS-QFIPXVFZSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50249293   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataIC50:  20nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataIC50:  12.8nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataEC50:  117nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataIC50:  11.7nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249293((R)-2-amino-2-(4-(4-(4-phenylbutoxy)phenyl)-1H-imi...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed