BDBM50250019 CHEMBL524658::PACAP::PACAP(1-38)::PACAP-38::PACAP38

SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=UFTCZKMBJOPXDM-XXFCQBPRSA-N

Data  7 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50250019   

LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataIC50:  0.0500nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique

Curated by ChEMBL
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataIC50:  6.10nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique

Curated by ChEMBL
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50250019(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)
Affinity DataIC50:  0.0400nMAssay Description:Displacement of [125I]PACAP1-27 from human recombinant PAC1 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed