BDBM50250074 CHEMBL507480::[Bip6]PACAP27
SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
InChI Key InChIKey=HVFBYLQDWMQSMM-FOKAWQFJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50250074
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique
Curated by ChEMBL
Institut National De La Recherche Scientifique
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC2 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique
Curated by ChEMBL
Institut National De La Recherche Scientifique
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair