BDBM50254851 3-Cyclohexyl-1-[4'-((3R,5S)-3,5-dimethyl-piperazin-1-ylmethyl)-biphenyl-2-ylmethyl]-1-[2-(3-methoxy-phenyl)-ethyl]-urea::3-cyclohexyl-1-((4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)biphenyl-2-yl)methyl)-1-(3-methoxyphenethyl)urea::CHEMBL501315
SMILES COc1cccc(CCN(Cc2ccccc2-c2ccc(CN3C[C@H](C)N[C@H](C)C3)cc2)C(=O)NC2CCCCC2)c1
InChI Key InChIKey=GNURRCJPQXKFTN-HNRBIFIRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50254851
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP3A4 (unknown origin) using phenylpiperazinylmethylbenzylresofurin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 50.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by calcium mobilization-based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Oryctolagus cuniculus)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 126nMAssay Description:Activity at ghrelin receptor in New Zealand White rabbit gastric antral smooth muscle by calcium mobilization-based FLIPR assayMore data for this Ligand-Target Pair