BDBM50255850 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole::CHEMBL481512

SMILES CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)[C@@H]1CCCNC1

InChI Key InChIKey=CYYNMPPFEJPBJD-OAQYLSRUSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50255850   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataKi:  0.0858nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataKi:  1.10nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]enadoline from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataKi: >667nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255850(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed