BDBM50256359 CHEMBL4064625

SMILES CCS(=O)(=O)Nc1ccc(Oc2ccccc2)c(c1)-c1[nH]c(C)c2c1cn[nH]c2=O

InChI Key InChIKey=YYFWVXHZOKCWDD-UHFFFAOYSA-N

Data  1 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256359   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50256359(CHEMBL4064625)
Affinity DataKi:  10nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50256359(CHEMBL4064625)
Affinity DataEC50:  75nMAssay Description:Inhibition of human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair