BDBM50258030 (S)-N-(2-chloro-4-(N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL492798

SMILES CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=LRIXMTVCKAOMMS-INIZCTEOSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258030   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258030((S)-N-(2-chloro-4-(N-methylphenylsulfonamido)pheny...)
Affinity DataEC50:  959nMAssay Description:Agonist activity at human LXRbeta expressed in human SH-SY5Y cells co-transfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258030((S)-N-(2-chloro-4-(N-methylphenylsulfonamido)pheny...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at LXRalpha ligand binding domain by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258030((S)-N-(2-chloro-4-(N-methylphenylsulfonamido)pheny...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human LXRalpha expressed in human SH-SY5Y cells cotransfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258030((S)-N-(2-chloro-4-(N-methylphenylsulfonamido)pheny...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at LXRbeta ligand binding domain (unknown origin) by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed