BDBM50262244 1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one::CHEMBL469198

SMILES O=C(CCCCCCc1ccccc1)c1nc(no1)-c1ccccn1

InChI Key InChIKey=PCUUQIVCWXAMBS-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50262244   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  0.340nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of human recombinant FAAH expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  3nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataKi:  3nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262244(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed