BDBM50265951 CHEMBL1657::TAZAROTENE::US9963439, Tazarotene::ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate

SMILES CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1

InChI Key InChIKey=OGQICQVSFDPSEI-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265951   

TargetRetinoic acid receptor gamma(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50265951(CHEMBL1657 | TAZAROTENE | US9963439, Tazarotene | ...)
Affinity DataEC50:  40nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50265951(CHEMBL1657 | TAZAROTENE | US9963439, Tazarotene | ...)
Affinity DataEC50:  63nMAssay Description:Activity at human RARalpha ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRetinoic acid receptor beta(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50265951(CHEMBL1657 | TAZAROTENE | US9963439, Tazarotene | ...)
Affinity DataEC50:  0.800nMAssay Description:Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank