BDBM50267883 8-Benzyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yloxy)-8-aza-bicyclo[3.2.1]octane::CHEMBL491861

SMILES C(N1C2CCC1CC(C2)OC1c2ccccc2CCc2ccccc12)c1ccccc1

InChI Key InChIKey=DZOFIEFQFCWGIY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267883   

LigandPNGBDBM50267883(8-Benzyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohept...)
Affinity DataIC50: 460nMAssay Description:Activity at human alpha4beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-evoked currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50267883(8-Benzyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohept...)
Affinity DataIC50: 1.73E+3nMAssay Description:Activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-evoked currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed