BDBM50269376 CHEMBL4082743
SMILES Nc1nc(Nc2ccc(N3CCN(CC3)C3CC4CCC3C4)c(Cl)c2)nn1-c1ncnc2sccc12
InChI Key InChIKey=VZOLHGIHSNGTLK-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50269376
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Rigel Pharmaceuticals
Curated by ChEMBL
Rigel Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 85nMAssay Description:Inhibition of Axl in human HeLa cells assessed as reduction in AKT phosphorylation at Ser 473 residues pre-incubated for 1 hr before preclustered ant...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Rigel Pharmaceuticals
Curated by ChEMBL
Rigel Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Inhibition of VEGF stimulated VEGFR2 phosphorylation at Y165 residues in HUVEC preincubated for 1 hr followed by VEGF addition measured after 5 mins ...More data for this Ligand-Target Pair