BDBM50270054 CHEMBL502642::TPRARRRKKRT

SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](-[#7])=O

InChI Key InChIKey=XIHRZTWKTVFWSV-HQSWAJDZSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50270054   

TargetFurin(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50270054(CHEMBL502642 | TPRARRRKKRT)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant furin assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 7(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50270054(CHEMBL502642 | TPRARRRKKRT)
Affinity DataKi:  135nMAssay Description:Inhibition of human recombinant PC7 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 6(Rattus norvegicus)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50270054(CHEMBL502642 | TPRARRRKKRT)
Affinity DataKi:  162nMAssay Description:Inhibition of rat PACE4 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50270054(CHEMBL502642 | TPRARRRKKRT)
Affinity DataKi:  232nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 4(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50270054(CHEMBL502642 | TPRARRRKKRT)
Affinity DataKi:  441nMAssay Description:Inhibition of human recombinant PC4 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed