BDBM50270615 CHEMBL521286::N-(4-chloro-3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-2-(trifluoromethyl)benzamide

SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)c2ccccc2C(F)(F)F)ccc1Cl

InChI Key InChIKey=AUJMYBVVKPOWGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270615   

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50270615(N-(4-chloro-3-(5-methylbenzo[d]oxazol-2-yl)phenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50270615(N-(4-chloro-3-(5-methylbenzo[d]oxazol-2-yl)phenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50270615(N-(4-chloro-3-(5-methylbenzo[d]oxazol-2-yl)phenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed