BDBM50271086 6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-methylene]-4H-isoquinoline-1,3-dione::CHEMBL484288

SMILES COc1ccc2C(=O)NC(=O)C(=CNc3ccc(CN4CCCCC4)cc3)c2c1

InChI Key InChIKey=ZIZIUNBOJMLGEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271086   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50271086(6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in Sf9 cells-baculovirus system assessed as retinoblastoma susceptibility gene product phospho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50271086(6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) expressed in Sf9 cells-baculovirus system assessed as retinoblastoma susceptibility gene product phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50271086(6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) expressed in Sf9 cells-baculovirus system assessed as retinoblastoma susceptibility gene product phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed