BDBM50271830 2-Benzyl-isothiourea::CHEMBL1224309::CHEMBL505665

SMILES NC(=N)SCc1ccccc1

InChI Key InChIKey=GTRLQRHWPXEBLF-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50271830   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto de Química Médica

Curated by ChEMBL
LigandPNGBDBM50271830(2-Benzyl-isothiourea | CHEMBL1224309 | CHEMBL50566...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50271830(2-Benzyl-isothiourea | CHEMBL1224309 | CHEMBL50566...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of recombinant human IDO using L-tryptophan as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50271830(2-Benzyl-isothiourea | CHEMBL1224309 | CHEMBL50566...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50271830(2-Benzyl-isothiourea | CHEMBL1224309 | CHEMBL50566...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of IDO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Okayama University

Curated by ChEMBL
LigandPNGBDBM50271830(2-Benzyl-isothiourea | CHEMBL1224309 | CHEMBL50566...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of indoleamine-2,3-dioxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed