BDBM50274952 CHEMBL512551::ethyl 5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carboxylate

SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)C1(Cc2ccccc2)CCNC1

InChI Key InChIKey=JIQNPRNQHOWEMG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274952   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(CHEMBL512551 | ethyl 5-(3-benzylpyrrolidin-3-yl)-1...)
Affinity DataKi:  4nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(CHEMBL512551 | ethyl 5-(3-benzylpyrrolidin-3-yl)-1...)
Affinity DataKi:  19nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(CHEMBL512551 | ethyl 5-(3-benzylpyrrolidin-3-yl)-1...)
Affinity DataKi:  38nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274952(CHEMBL512551 | ethyl 5-(3-benzylpyrrolidin-3-yl)-1...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed