BDBM50277186 (R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-2-yl)propyl dihydrogen phosphate::CHEMBL474689

SMILES CCCCCCCCOc1ccc(cc1)-c1c[nH]c(n1)[C@@](C)(N)COP(O)(O)=O

InChI Key InChIKey=JJPKCGYTCKVOEU-FQEVSTJZSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277186   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataEC50:  14.8nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277186((R)-2-amino-2-(4-(4-(octyloxy)phenyl)-1H-imidazol-...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed