BDBM50287549 5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::5-(2-Cyclopropylmethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL52141

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC1CC1

InChI Key InChIKey=DOEKANBUIKUFKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287549   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  960nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  955nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed