BDBM50287989 CHEMBL4173588

SMILES C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)c1cccc(NC(N)=N)c1)c1ccccc1

InChI Key InChIKey=QYKHSZCOMAXNCJ-GUYCJALGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287989   

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50:  20nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50:  270nMAssay Description:Displacement of p53 from MDM2 in human U87MG cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed