BDBM50288530 CHEMBL4098253

SMILES COC1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=HYNBNUYQTQIHJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288530   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed