BDBM50288590 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid (S)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester::CHEMBL92100

SMILES Nc1c2CCOc2c(cc1Cl)C(=O)O[C@@H]1CN2CCC1CC2

InChI Key InChIKey=QUSHSFRRPJRJKS-CYBMUJFWSA-N

Data  2 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288590   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288590(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Show SMILES Nc1c2CCOc2c(cc1Cl)C(=O)O[C@@H]1CN2CCC1CC2
Show InChI InChI=1S/C16H19ClN2O3/c17-12-7-11(15-10(14(12)18)3-6-21-15)16(20)22-13-8-19-4-1-9(13)2-5-19/h7,9,13H,1-6,8,18H2/t13-/m1/s1
Affinity DataKi:  0.200nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288590(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Show SMILES Nc1c2CCOc2c(cc1Cl)C(=O)O[C@@H]1CN2CCC1CC2
Show InChI InChI=1S/C16H19ClN2O3/c17-12-7-11(15-10(14(12)18)3-6-21-15)16(20)22-13-8-19-4-1-9(13)2-5-19/h7,9,13H,1-6,8,18H2/t13-/m1/s1
Affinity DataKi:  8.30nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288590(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Show SMILES Nc1c2CCOc2c(cc1Cl)C(=O)O[C@@H]1CN2CCC1CC2
Show InChI InChI=1S/C16H19ClN2O3/c17-12-7-11(15-10(14(12)18)3-6-21-15)16(20)22-13-8-19-4-1-9(13)2-5-19/h7,9,13H,1-6,8,18H2/t13-/m1/s1
Affinity DataEC50:  11nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In DepthDetails Article