BDBM50288934 2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-oxy-(3-methyltetrahydro-2H-4,5,6-pyrantriol)-5-methylcarboxamidotetrahydro-2H-3-pyranyloxy)-6-hydroxymethyltetrahydro-2H-4-pyranyloxy]-4-hydroxy-5-methylcarboxamido-6-(1,2,3-trihydroxypropyl)tetrahydro-2H-2-pyrancarboxylic acid::5-Acetylamino-2-[[2-(5-acetylamino-4,6-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy)-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy]-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)]-4-hydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid::5-Acetylamino-2-{2-[5-acetylamino-2-hydroxy-4-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy}-4-hydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid::5-Acetylamino-2-{2-[5-acetylamino-6-hydroxy-2-hydroxymethyl-4-(3,4,5-trihydroxy-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-3,5,6-trihydroxy-tetrahydro-pyran-4-yloxy}-4-hydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid::CHEMBL31535::Sialyl LeX::Sialyl Lewis X Analog(sLeX)::Sialyl Lewis X Mimetic::Sialyl Lewis x (sLex)::Sialyl lewis-x::sLex::sialyl Lewis X(sLe x)

SMILES CC1OC(OC2C(NC(C)=O)C(O)OC(CO)C2OC2OC(CO)C(O)C(OC3(CC(O)C(NC(C)=O)C(O3)[C@@H](O)[C@H](O)CO)C(O)=O)C2O)C(O)C(O)C1O

InChI Key InChIKey=NIGUVXFURDGQKZ-QFEWMJNOSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50288934   

TargetP-selectin(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50: >1.00E+6nMAssay Description:Blocking activity on Selectin P ligand bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against P-selectin using ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Mus musculus)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50:  5.80E+5nMAssay Description:Evaluated for the inhibitory activity against Selectin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50:  3.40E+6nMAssay Description:Inhibition of P-selectin in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Revotar Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50:  1.34E+5nMAssay Description:Inhibition of human E-selectin after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-selectin(Homo sapiens (Human))
Revotar Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50: >4.00E+6nMAssay Description:Inhibition of human L-selectin after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin glycoprotein ligand 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50:  1.50E+7nMAssay Description:Inhibition of recombinant PSGL-1 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50288934(2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...)
Affinity DataIC50: >4.00E+6nMAssay Description:Inhibition of human P-selectin after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed