BDBM50289703 Lumacaftor::VRT 826809::VRT-826809::VX 809::VX-809

SMILES Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O

InChI Key InChIKey=UFSKUSARDNFIRC-UHFFFAOYSA-N

Data  2 IC50  2 Kd  4 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289703   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataEC50:  2.60E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin)More data for this Ligand-Target Pair