BDBM50291970 3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL150052

SMILES C[C@@H]1CN(C\C=C\c2ccccc2)CC[C@]1(C)c1cccc(O)c1

InChI Key InChIKey=SUIRCGLIUIROIR-FIHPSEJCSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50291970   

TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  0.0390nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor mu 1 in Guinea pig Caudate stimulated by DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  0.740nMAssay Description:Binding affinity determined on Opioid receptor mu 1 in Guinea pig brain membranes using radioligand [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  1nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor kappa 1 in Guinea pig Caudate stimulated by U69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor delta 1 in Guinea pig Caudate stimulated by SNC80More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  122nMAssay Description:Binding affinity determined on Opioid receptor kappa 1 in Guinea pig brain membranes using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50291970(3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-pip...)
Affinity DataKi:  322nMAssay Description:Binding affinity determined on Opioid receptor delta 1 in Guinea pig brain membranes using radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed