BDBM50293279 1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyrrolo[1,2-a]thieno[2,3-e]pyrazine::CHEMBL470432

SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1

InChI Key InChIKey=FZGWDCDUMFWUEO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293279   

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Affinity DataKi:  1.74nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Affinity DataIC50:  385nMAssay Description:Antagonist activity at 5HT3 receptor in hybrid NG108-15 cells assessed as inhibition of 5HT-induced current by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Affinity DataIC50:  6.92nMAssay Description:Displacement of [3H]granisetron from human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed