BDBM50294733 CHEMBL558494::N-[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]-N-[(1-methyl-1H-indol-7-yl)methyl]amine

SMILES Cn1ccc2cccc(CNc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(Cl)cccc34)c12

InChI Key InChIKey=RXAWOIWCWMZXHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294733   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294733(CHEMBL558494 | N-[3-(3-Benzyl-8-chlorocinnolin-4-y...)
Affinity DataIC50: >1.00E+6nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294733(CHEMBL558494 | N-[3-(3-Benzyl-8-chlorocinnolin-4-y...)
Affinity DataIC50:  2.40E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed