BDBM50294735 CHEMBL558495::[3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(1-methyl-1H-indol-7-yl)methyl]amine

SMILES Cn1ccc2cccc(CNc3cccc(c3)-c3c(nnc4c(Cl)cccc34)-c3ccccc3)c12

InChI Key InChIKey=DFDLNHGSXIIXAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294735   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294735(CHEMBL558495 | [3-(8-Chloro-3-phenylcinnolin-4-yl)...)
Affinity DataIC50:  6.20E+4nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294735(CHEMBL558495 | [3-(8-Chloro-3-phenylcinnolin-4-yl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed