BDBM50294739 CHEMBL549892::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-(1H-indol-7-ylmethyl)amine

SMILES FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(NCc2cccc3cc[nH]c23)c1

InChI Key InChIKey=RLNNMCHGUCZOSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294739   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294739(CHEMBL549892 | {3-[3-Benzyl-8-(trifluoromethyl)qui...)
Affinity DataIC50:  1.34E+5nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294739(CHEMBL549892 | {3-[3-Benzyl-8-(trifluoromethyl)qui...)
Affinity DataIC50:  3.80E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed