BDBM50294756 3-Benzyl-4-{3-[(1-methyl-1H-indol-2-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline::CHEMBL561450

SMILES Cn1c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)cc2ccccc12

InChI Key InChIKey=IOWZLHRNMKWCPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294756   

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294756(3-Benzyl-4-{3-[(1-methyl-1H-indol-2-yl)methoxy]-ph...)
Affinity DataIC50: >1.00E+6nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294756(3-Benzyl-4-{3-[(1-methyl-1H-indol-2-yl)methoxy]-ph...)
Affinity DataIC50:  4.20E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed