BDBM50295769 CHEMBL564827::tert-butyl 4-(4-(1-(benzo[c][1,2,5]oxadiazol-4-ylmethyl)-1H-pyrrolo[3,2-b]pyridin-6-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc2ccn(Cc3cccc4nonc34)c2c1

InChI Key InChIKey=SKESEUVJTIJZFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295769   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295769(CHEMBL564827 | tert-butyl 4-(4-(1-(benzo[c][1,2,5]...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295769(CHEMBL564827 | tert-butyl 4-(4-(1-(benzo[c][1,2,5]...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295769(CHEMBL564827 | tert-butyl 4-(4-(1-(benzo[c][1,2,5]...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295769(CHEMBL564827 | tert-butyl 4-(4-(1-(benzo[c][1,2,5]...)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed