BDBM50296005 CHEMBL564824::methyl 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoate

SMILES COC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=AXQNDKWNRKTQRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296005   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296005(CHEMBL564824 | methyl 4-(5-phenyl-1H-pyrrolo[2,3-b...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296005(CHEMBL564824 | methyl 4-(5-phenyl-1H-pyrrolo[2,3-b...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed